Chromium-based browsers like Google Chrome and Microsoft Edge use Chromium built-in DNS resolver by default instead of the system resolver. This results in Apple configuration profiles (on macOS), system-wide DNS over HTTPS (on Windows), and DDR encrypted upgrade (on both macOS and Windows) being ignored.Those issues have been raised with the Chromium team:
You can manually disable the Chromium built-in resolver by opening chrome://flags/#enable-async-dns and disabling the Async DNS resolver flag. You will be asked to relaunch your browser after doing this.